Sindrome de evans pdf

Evans syndrome, thrombocytopenia, autoimmune hemolytic anemia, pregnancy. Evans, syndrome, hemolytic anemia, thrombocytope nia, neutropenia. In the initial description by evans et al in 1951, the anemia and thrombocytopenia varied with respect to time of onset, course, and duration. Surge quando os anticorpos produzidos pelo corpo atacam o. Our patient is a girl 10 month old with evanss syndrome, lymphopenia, antinuclear antibodies, antidna antibodies, lupus anticoagulant and anticardiolipin antibodies. In the initial description by evans et al in 1951, the anemia and thrombocytopenia varied with respect to. Previously, it was known as the simultaneous or sequential development of primary immune thrombocytopenia and autoimmune hemolytic anemia 2. Management of evans syndrome uw hematology protocols. Etiology evans syndrome is an autoimmune disorder in which noncrossreacting autoantibodies are targeted towards different antigenic determinants on red cells, platelets, sometimes neutrophils. Evans syndrome in patients with secondary antiphospholipid. Systemic lupus erythematosus and antiphospholipid syndromes are infrequent conditions in children under 5 years. Although few statistical data are available, it has been reported that between and 73% of patients with autoimmune hemolytic.

This familial disease is associated with a high lifetime risk of esophageal cancer. Evans syndrome is a rare diagnosis although the exact frequency is unknown. Alguns pacientes com esta doenca podem ter apenas as celulas brancas destruidas ou apenas as celulas vermelhas, mas toda a. E uma doenca cronica e recidivante associada a morbidade significativa, apesar da terapeutica. These immune cytopenias may occur simultaneously or sequentially. Its overall phenotype resembles a combination of autoimmune hemolytic anemia and immune thrombocytopenic purpura. Evans syndrome is characterized by the reduction of at least two blood cell. Evans syndrome is an autoimmune disease in which an individuals immune system attacks their own red blood cells and platelets, the syndrome can include immune neutropenia.